Spero Chemical Imaging Microscope

SPERO

Mid-IR Chemical Imaging Microscope

In a class of their own, the Spero® microscopes are the world’s first and only fully integrated, wide-field spectroscopic microscopy and imaging platforms based on our broadly tunable mid-infrared quantum cascade laser technology.

Spero-QT

The Spero-QT microscope is the second-generation platform in this new class of instruments with high-performance, label-free chemical imaging. The Spero system offers unrivaled mid-IR spectroscopy, substantially outperforming FTIR microscopes in spatial resolution, speed, and field-of-view capabilities while eliminating the need for cryogenic cooling. This system is faster than Raman or Phothermal IR microscopes, by orders of magnitude, while avoiding the issues of sample auto-fluorescence. Using a proprietary wide-field, low-noise instrument architecture, the Spero microscopes enable new data collection modalities such as live, real-time chemical imaging and user-defined sparse discrete frequency data collection. Their small desktop footprints make them suitable for labs with space constraints. The Spero-QT system has the wide-field, high-resolution attributes of its predecessor but with the capability to produce twice the data in one-tenth of the time, while achieving unprecedented signal-to-noise ratios. The Spero-QT stage can image up to 3 microscope slides, and its larger sample compartment makes the Spero-QT more compatible with microfluidic devices and accessories.

Spero-LT

The Spero-LT is the latest model in the Spero product family. The LT offers the same high-performance speed and resolution specifications as the Spero-QT flagship model but is economically configured to address a wide range of materials and life sciences research applications while fitting within tight budget constraints. Contact us to learn what configuration options are available.

FEATURES

Real-Time Analysis

Real-Time Analysis

Infrared imaging at video rate speed

Non-Destructive

Non-Destructive

No labels, stains, or molecular tags

Quantitative Data

Quantitative Data

Hyperspectral data at each pixel

Simplified Workflow

Simplified Workflow

Minimal tissue preparation for analysis

APPLICATIONS

Cancer Research

Researchers have shown the ability to render accurate tumor margin analysis and cancer sub-typing of fresh frozen sections in minutes using the Spero microscope

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Fibrosis

IR imaging is a potentially powerful adjunct to current pathology practice, with the ability to visualize fibrosis in tissues and extract novel biomarkers that can predict the progression of fibrosis

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Neurodegenerative Diseases

Infrared sensing is highly specific in characterizing proteins and presents a promising future of early intervention of neurodegenerative diseases

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