QCL-IR for Drug Research and Production

Biophysical Characterization

QCL-IR Spectroscopic Solutions for Drug Discovery, Development and Production

Current demands in the biopharmaceutical market are to bring novel drugs to the market faster, more cost-effectively, and with better quality. There is an active trend towards in-line biophysical characterization of a drug product by minimizing the lead time. Mid-IR spectroscopy, with an added benefit of QCL-IR technology, can unlock your potential to achieve rapid biophysical characterization of biotherapeutics.

Mid-IR absorption spectroscopy is already a widely accepted analytical technique by the pharmaceutical industry and its associated regulatory bodies. Traditionally, FT-IR instruments have been the workhorse tool for mid-IR analysis, but these technologies have been unable to address emerging needs for the real-time and highly sensitive PAT (Process Analytical Technologies) workflow due to the low spectral brightness of its light source.

The Culpeo® liquid analyzer platform is a purpose-built technological solution for the biopharmaceutical industry. Culpeo may be implemented into a wide range of sampling interfaces (in-line, at-line, walk-up, batch) to characterize fractionated or un-fractionated analytes in a complex matrix. This platform enables easy method development and subsequent method transfer to downstream groups with minimal method optimizations. Explore the selected applications below, and contact us to find out how we can assist you.

Data Sheet
Interested in our capabilities?

Download the data sheet to learn more about the Culpeo QCL-IR Analyzer.

Download +

Want to learn more?

Download our free e-book for an introduction to mid-IR liquid analyzers for pharmaceutical applications.

Download +


Bioprocess Analytics

Culpeo easily couples with commonly used sampling interfaces connected to bioreactors to support biophysical characterization

Learn more +

Protein Analytics

Culpeo can be used to perform rapid, direct quantitation and characterization of secondary structure

Learn more +

Liquid Chromatography

Culpeo works seamlessly with a broad array of commercially available liquid chromatography systems, enabling time-resolved spectroscopic measurements of both fractionated and non-fractionated fluids

Learn more +

Vaccine Bioprocess

Culpeo allows real-time measurements and data output that can be used for quantitating secondary structures of vaccine drug products

Learn more +